Floratil Special Precautions

If symptoms persist for more than two days of treatment at usual posology, the therapeutic approach will be reevaluated.
Saccharomyces boulardii (Floratil) contains living cells. This drug should therefore not be mixed with very hot (over 50°C), iced or alcoholic drinks or food.
The treatment does not replace rehydration when this is necessary. The rehydration dose and its route of administration (oral-IV) should be adapted to the severity of the diarrhea and to the age and state of health of the patient.
It is advisable not to open the capsule or sachet in the surroundings of patients with a central venous catheter, to avoid colonization, especially hand-borne, of the catheter. There have been reports in patients with a central venous catheter, even not treated with S. boulardii, of very rare cases of fungemia (penetration of blood by yeast), most often resulting in pyrexia and blood cultures positive for Saccharomyces. The outcome in all these cases has been satisfactory after administration of antifungal treatment and, when necessary, removal of the catheter.
Because of the presence of lactose, Saccharomyces boulardii (Floratil) is contraindicated in patients suffering from congenital galactosemia, glucose and galactose malabsorption syndrome or lactase deficit.
Because of the presence of fructose, Saccharomyces boulardii (Floratil) sachet is contraindicated in case of fructose intolerance.