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Animal studies with orally and parenterally administered Co-Amoxiclav (COBIOMAX) have shown no teratogenics effects. The safety evidence for use in pregnancy has not been established, therefore the drug should not be administered to pregnant patients or women suspected of being pregnant esp. during the 1st trimester, except that the expected therapeutic benefit is thought to outweigh any possible risk.
During lactation, trace quantities of penicillin can be excreted in breast milk.
