Use in Lactation: Cefoxitin is distributed into breast milk but is detectable only in low concentrations. In a study in which cefoxitin was given prophylactically in doses of 2 to 4 g to 18 women undergoing caesarean section, only one sample of breast milk contained measurable concentrations of cefoxitin, 19 hours after the last dose. No adverse effects have been observed in breast-fed infants whose mothers were receiving cefoxitin, and the American Academy of Pediatrics considers that it is therefore usually compatible with breast feeding.
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