Because of the activity of Cefoxitin against Bacteroides fragilis and other anaerobic bacteria, it is used principally in the treatment and prophylaxis of anaerobic and mixed bacterial infections, especially intra-abdominal and pelvic infections. Indications include endometritis (prophylaxis at caesarean section), pelvic inflammatory disease, and surgical infection (prophylaxis). It may also be used in the treatment of gonorrhoea and urinary-tract infections.