Not to be given to patients w/ angle-closure glaucoma or w/ narrow angle between the iris & the cornea. Isolated instances of mental confusion, euphoria, agitation & disturbed behaviour. Risk of central anticholinergic syndrome. Patients w/ manifest glaucoma; prostatism, epilepsy or cardiac arrhythmia; acute MI & HTN. May raise IOP & precipitate acute attack. Caution in conditions characterized by tachycardia eg, thyrotoxicosis, heart failure, & in cardiac surgery. May cause confusion. Reduced bronchial secretion. Avoid abrupt w/drawal. Avoid consumption of alcohol during therapy. Drowsiness may occasionally occur which may affect ability to drive or operate machinery. Pregnancy & lactation. Safety & effectiveness have not been established in childn. Elderly.