Benadryl One Adverse Reactions

Cetirizine hydrochloride (Benadryl One), though considered as a "non-sedating" antihistamine, was found to cause drowsiness in some people.
Recurrent acute hepatitis developed in one patient taking Cetirizine hydrochloride (Benadryl One) for control of seasonal allergic rhinitis.
Other adverse effects associated with the use of Cetirizine hydrochloride are irritability, insomnia, somnolence, fatigue, dry mouth, pharyngitis, dizziness, headache, abdominal pain, cough, diarrhea, epistaxis, bronchospasm, nausea and vomiting and hypersensitivity manifested by urticarial and fixed drug eruptions.
Although Cetirizine hydrochloride has low potential for hepatotoxicity, the possibility of developing autoimmune-mediated hepatotoxicity should be considered when administering the drug. A patient under long-term treatment with Cetirizine hydrochloride (Benadryl One) for atopic dermatitis was reported to have developed life-threatening hepatitis.