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There is limited clinical experience of accidental overdose. In animal studies, Anastrozole demonstrated low acute toxicity.
In the management of an overdose, consideration should be given to the possibility that multiple agents may have been taken. Absorption can be lowered by gastric lavage followed by administration of activated charcoal or charcoal. Dialysis may be helpful because Anastrozole is not highly protein bound. General supportive care, including frequent monitoring of vital signs and close observation of the patient, is indicated.
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