Cardiovascular: Angina pectoris, second degree AV block, arrhythmias including atrial fibrillation, cardiovascular accident (CVA), hypotension/orthostatic hypotension, myocardial infarction, palpitation, sinus bradycardia, tachycardia, ventricular tachycardia, ventricular fibrillation.
Endocrine: Diabetic neuropathy, diabetic vascular disease.
Gastrointestinal: Abdominal pain, anorexia, constipation, dental pain, diarrhea, dry mouth, dyspepsia, flatulence, gastritis, pancreatitis, nausea, vomiting.
Genitourinary: Erectile dysfunction/impotence, nocturia, renal impairment, renal failure, urinary frequency, urinary tract infection.
Hematologic: Hemolysis, anemia, thrombocytopenia (rare).
Hepatobiliary: Liver function abnormalities, hepatitis (rare).
Hypersensitivity: Anaphylactic reactions, angioedema (including swelling of the larynx and glotitis, causing airway obstruction and or swelling of the face, lips, pharynx, and/or tongue), vasculitis including Henoch-Schönlein purpura (rare).
Metabolic and Nutritional and Laboratory Values: Gout, hyperkalemia, hypoglycemia, hyponatremia, weight gain; Elevations of the following: alanine aminotransferase (ALT), BUN, serum creatinine, liver enzymes and/or bilirubin; Reductions of the following: hemoglobin and hematocrit.
Musculoskeletal: Arthralgia, arthritis, fibromyalgia, joint swelling, myalgia, muscle cramps, muscle weakness, pain (back, arm, shoulder, hip, leg, knee, musculoskeletal), stiffness, rhabdomyolysis (rare).
Nervous System/Psychiatric: Dizziness, anxiety, anxiety disorder, ataxia, confusion, depression, dream abnormality, dysgeusia, headache, hypesthesia, insomnia, decreased libido, memory impairment, migraine, nervousness, panic disorder, paresthesia, peripheral neuropathy, sleep disorder, somnolence, tremor, vertigo.
Respiratory: Bronchitis, cough/dry cough, dyspnea, epistaxis, nasal congestion, respiratory congestion, pharyngeal discomfort, pharyngitis, rhinitis, sinusitis, sinus disorder, upper respiratory tract infections.
Skin: Alopecia, cellulitis, dermatitis, dry skin, ecchymosis, erythema, erythroderma, flushing, photosensitivity, pruritus, rash, sweating, superficial peeling of palms, urticaria.
Special senses: Blurred vision, burning/stinging in the eye, cataract, conjunctivitis, tinnitus, decreased visual acuity.
Amlodipine besilate: The most commonly reported adverse reactions during treatment with amlodipine are somnolence, dizziness, headache, palpitations, flushing, abdominal pain, nausea, ankle swelling, edema and fatigue.
Body as a Whole: Asthenia, chest pain, edema/swelling, fatigue, malaise, pain, peripheral edema, rigors.
Cardiovascular: Arrhythmia (including ventricular tachycardia and atrial fibrillation), bradycardia, flushing, hypotension, hot flushes, myocardial infarction, palpitation, peripheral ischemia, syncope, tachycardia, vasculitis.
Gastrointestinal: Abdominal pain altered bowel habits, anorexia, constipation, diarrhea, dry mouth, dyspepsia, dysphagia, flatulence, gastritis, gingival hyperplasia, nausea, pancreatitis, vomiting.
Genitourinary: Gynecomastia, impotence, micturition frequency, micturition disorder, nocturia, sexual dysfunction.
Hematologic: Thrombocytopenia, leukopenia.
Hepatobiliary: Hepatic enzyme elevations (mostly consistent with cholestasis), hepatitis, jaundice.
Hypersensitivity: Allergic reactions.
Metabolic: Hyperglycemia, thirst, weight increase/decrease.
Musculoskeletal: Ankle swelling, arthralgia, arthrosis, back pain, muscle cramps, myalgia.
Nervous System: Abnormal dreams, anxiety, confusion, depersonalization, dysgeusia, depression, dizziness, extrapyramidal disorder, headache, hypertonia, hypoesthesia, insomnia, mood changes, nervousness, paresthesia, peripheral neuropathy, somnolence, tremor, vertigo.
Respiratory: Cough, dyspnea, epistaxis, rhinitis.
Skin: Alopecia, angioedema, exanthema, erythema multiforme, exfoliative dermatitis, hyperhidrosis, purpura, pruritus, photosensitivity, rash, rash erythematous, rash maculopapular, skin discoloration, urticaria, Stevens-Johnson syndrome (very rare), Quincke edema (very rare).
Special senses: Conjunctivitis, diplopia, eye pain, tinnitus, abnormal vision, visual disturbances.
View ADR Reporting Link