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Adverse reactions to local anaesthetics in the true sense of the term, occur in <1/1000 of those treated.
Common (>1/100): Skin: Transient local skin reactions at the application site e.g. local paleness, redness, oedema.
Uncommon (1/100-1/1000): Skin: Initially slight smarting, itching (at the application site).
Rare (<1/1000): General: Allergic reactions, in the most severe cases, anaphylactic shock.
Methaemoglobin in children.
Rare cases of discrete actions at the application site (e.g. purpura or pethechiae), have been reported, especially after prolonged application times in children with atopic dermatitis or warts.
In cases of accidental contact with the eye, corneal irritation can occur.
