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RACSER Cream may cause an increase in the formation of methaemoglobin in patients treated with methaemoglobin-inducing drugs (e.g. sulphonamides).
With large doses RACSER Cream, consideration should be given to the risk of additional systemic toxicity in patients receiving other local anesthetics or agents structurally related to local anaesthetics (e.g. tocainide), since the toxic effects are additive.
There are no specific interaction studies with local anaesthetics and class III antiarrhythmic drugs (e.g. amiodarone) carried out, but caution is recommended.
