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Hypersensitivity of Cephalosporin antibiotics. In patients hypersensitive to penicillin, the allergic cross-reactions may occur.
Ceftriaxone is contraindicated in neonates (≤28 days of age) if they require (or are expected to require) treatment with calcium-containing intravenous solutions, including calcium-containing infusions such as parenteral nutrition, because of the risk of precipitation of ceftriaxone-calcium.
