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Usage has not been established in depression with psychosis features, in bipolar disorders or in "endogenous" depression (i.e., severely depressed in-patients).
Habituation and emotional/physical dependence may occur with Benzodiazepines, including Alprazolam.
Caution should be particularly used when prescribing Benzodiazepines to patients who are prone to abuse drugs (e.g., alcoholics and drug addicts) because of their predisposition to habituation and dependence.
ZOLYSAN 0.5 or 1 Caplet are not recommended for use inpatients whose primary diagnosis is schizophrenia.
Episodes of hypomania and mania have been reported in association with the use of Alprazolam in patients with depression.
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