Methadone Pliva Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Contraindications Warnings Special Precautions Adverse Reactions MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Methadone

Indications/Uses

Management of pain severe enough to require daily, around-the-clock, long-term opioid treatment & for which alternative treatment options are inadequate eg, severe pain when other drugs provide no relief (eg, carcinoma & other malignant diseases, in burns, MI, neuritis & severe neuralgia, biliary & renal colics, vesical tenesmus, post-op & post-traumatic pain).

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Dosage/Direction for Use

2.5 mg orally every 8-12 hr. Dosage must be carefully individualized according to patient response.

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Administration

May be taken with or without food.

Contraindications

Pregnancy; neurosurgical interventions; shock; copious bleeding. Patients should be advised not to take methadone 4 hr prior to driving a car or during driving.

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Warnings

For additional cautionary notes to warn of the potential risk of using the medicine... Click to view Methadone Pliva detailed prescribing information

Special Precautions

Not indicated as an as-needed analgesic. Do not increase the dose above the recommended & administer only for a limited period (except in cases of malignant processes). Concomitant use w/ benzodiazepines or other CNS depressants, including alcohol, may result in profound sedation, resp depression, coma, & death. Hypoglycaemia (unknown frequency) has been observed in the context of methadone overdose or dose escalation. Regular monitoring of blood sugar is recommended during dose escalation. Limit dosages & durations to the min required. Observe patients for signs & symptoms of resp depression & sedation. Accidental consumption of even 1 dose, especially by childn, can result in a fatal overdose. May impair ability to drive or operate machinery.

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Adverse Reactions

Resp depression & cardiac arrhythmias.

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Description

View Methadone Pliva description for details of the chemical structure and excipients (inactive components).

Action

View Methadone Pliva mechanism of action for pharmacodynamics and pharmacokinetics details.

MIMS Class

Analgesics (Opioid) / Supportive Care Therapy

ATC Classification

N07BC02 - methadone ; Belongs to the class of drugs used in the management of opioid dependence.

Regulatory Classification

DD, P₁S₁

Presentation/Packing

Form

Methadone Pliva tab 5 mg

Packing/Price

100's

Methadone Pliva

methadone

Manufacturer:

Pliva

Distributor:

DCH Auriga - Universal