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Silodosin is a substrate of CYP3A4 and P-glycoprotein.
Silodosin is a substrate of UDP-glucuronosyltransferase 2B7 (UGT2B7).
Concurrent use of silodosin and itraconazole, selected strong CYP3A4 inhibitors, or boceprevir may result in increased silodosin exposure.
Concurrent use of silodosin and cyclosporine may result in increased silodosin concentration.
Concurrent use of silodosin and tadalafil, sildenafil, or avanafil may result in increased risk of hypotension.
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