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Cyclosporine is a fine white powder. RESTASIS appears as a white opaque to slightly translucent homogeneous emulsion. It has an osmolality of 230-320 mOsmol/kg and a pH of 6.5-8.
Each mL of RESTASIS contains cyclosporine 0.05%.
RESTASIS (cyclosporine ophthalmic emulsion) 0.05% contains a topical immunomodulator with anti-inflammatory effects. Cyclosporine's chemical name is Cyclo[[(E)-(2S,3R,4R)-3-hydroxy-4-methyl-2-(methylamino)-6-octenoyl]-L-2-aminobutyryl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl]. It has a molecular formula of C62H111N11O12 and molecular weight of 1202.6.
Excipients/Inactive Ingredients: Glycerin, castor oil, polysorbate 80, carbomer 1342, purified water and sodium hydroxide to adjust the pH.
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