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No toxic overdose has yet been observed with oral pharmaceutical forms of acetylcysteine.
Voluntary study subjects were treated for three months with a dose of 11.6 g acetylcysteine per day without any serious undesirable effects being observed. Oral doses of up to 500 mg acetylcysteine per kg body weight were tolerated without any signs of poisoning.
Symptoms: Overdoses may lead to gastrointestinal effects such as nausea, vomiting and diarrhoea.
Management: Symptomatic treatment if necessary.
