NAC long Drug Interactions

The effect of some drugs may be influenced by contemporaneous application of other drugs. Therefore ask the doctor if the patient uses other drugs permanently, if the patient has used them recently or if the patient has to use them contemporaneously with the present drug. The physician is able to let the patient know whether the patient has to expect interactions under these circumstances or whether special measures e.g., a new dosage is necessary, in case the patient uses this drug.
Tetracycline hydrochloride should be administered separately and at least 2 hours apart (not valid for Doxycycline).
Antitussive agents should not be given concomitantly with acetylcysteine, because a decrease in the cough reflex may result in the accumulation of bronchial secretions.
The concomitant administration of acetylcysteine and nitroglycerin should be avoided because it induces hypotension. If concomitant administration cannot be avoided, patients should be monitored for hypotension and warned about the possible occurrence of hypotension and headache.