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Use with caution in patients with pre-existing liver disease; hepatic impairment with or without jaundice.
Discontinue if symptoms of malaise, nausea, vomiting, abdominal colic, and fever.
Allergic reactions have been reported (rare); reappearance of allergic reaction may occur without further azithromycin exposure.
Azithromycin may mask or delay symptoms of incubating gonorrhea or syphilis, so appropriate culture and susceptibility tests should be performed prior to initiating azithromycin.
Prolonged use may result in fungal or bacterial superinfection, including C. difficile-associated diarrhea (CDAD) and pseudomembranous colitis.
Use caution with renal dysfunction.
Prolongation of the QTc interval has been reported with macrolide antibiotics; use caution in patients at risk of prolonged cardiac repolarization.
Use with caution in patients with myasthenia gravis.
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