ChiroRab

Pre- & post-exposure immunization against rabies.

IM 1 mL/dose. Administer by IM inj into the deltoid muscle, or into the anterolateral region of the thigh in small childn. Pre-exposure immunization 1 dose on days 0, 7 & 21 (or 28). Post-exposure immunisation Unimmunised or incompletely immunised individuals 1 single dose on days 0, 3, 7, 14, 28. Alternatively, 2 doses on day 0 (as 1 dose into the right & left deltoid muscle, or in small childn, each into the anterolateral region of the right & left thigh), & 1 dose each on days 7 & 21. Previously fully immunized individuals 2 doses, 1 on each of days 0 & 3 (independent of interval to last immunization). Immunocompromised individuals Administer once on days 0, 3, 7, 14, 28. Initial dose (day 0) should be doubled w/ a single dose post-exposure. Intradermal inj 0.1 mL/dose. Administer in the upper arm over the deltoid. Non-vaccinated individuals 1 dose over each left & right deltoid on days 0, 3, 7, & 1 dose on upper arm on day 28 (or 30) & day 90. Alternatively, dose for day 90 can be administered as a 2nd dose on day 28 or 30. Fully vaccinated individuals Immediate booster dose on days 0, 3.

Hypersensitivity. Avoid pre-exposure immunisation in individuals w/ acute disorders requiring treatment.

Do not administer intravascularly & in the gluteal muscle. Hypersensitivity to antibiotics amphotericin B, chlortetracycline, neomycin. Not to be administered as intradermal inj in individuals receiving long-term corticosteroid or other immunosuppressive therapy or chloroquine; & in immunocompromised individuals. Carefully weigh benefits against potential risks prior to prophylaxis in pregnancy & lactation.

Inj site reactions eg, pain, redness, swelling, induration. Fever, headache, myalgia, lymph node swelling, fatigue, arthritis, GI disorders.

Immunosuppressives & antimalarials. Rabies Ig.

Vaccines, Antisera & Immunologicals

J07BG01 - rabies, inactivated, whole virus ; Belongs to the class of rabies viral vaccines.

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