Artrofort Complex Special Precautions

No important effects on the central nervous system or motor system are known that might impair the ability to drive or use machines. However, caution is advised if headache, somnolence, tiredness, dizziness, or visual disturbances are experienced.
This medicinal product contains sodium. To be taken into consideration by patients on a controlled sodium diet.
In patients with cardiac and/or renal insufficiency, edema and water retention was observed very rarely. This effect could be attributed to the effect of chondroitin sulphate. The administration of ARTROFORT Complex to these patients should be under strict medical supervision.
No special studies were performed in patients with hepatic insufficiency. The administration of ARTROFORT Complex to patients with severe hepatic insufficiency should be under strict medical supervision.
Caution is advised in treatment of patients with impaired glucose tolerance. Closer monitoring of blood sugar levels may be necessary at the beginning of treatment.
In asthmatic patients the product should be used with caution as these patients could be more susceptible to develop an allergic reaction to glucosamine with a possible exacerbation of their symptoms.
An increased effect of cumarinic anticoagulants (such as warfarin) during concomitant treatment with glucosamine sulphate, one of the active ingredients of ARTROFORT Complex, may occur. Therefore, a closer monitoring of the coagulation parameters may be considered in those patients being treated with ARTROFORT Complex.
Due to its chondroitin sulphate content, in case of concomitant administration of platelet anti-aggregant drugs such as acetyl salicylic acid, dipyridamol, clopidogrel, ditazol, trifusal and ticlopidine, ARTROFORT Complex should be administered under strict medical supervision.
Concurrent treatment with glucosamine sulphate may increase the gastro-intestinal absorption of tetracyclines. Caution is advised in case of concomitant administration of ARTROFORT Complex and tetracyclines.
Excipients: This medicinal product contains Sunset yellow FCF (E110), which may cause allergic reactions.
Use in Pregnancy & Lactation: See Use in Pregnancy & Lactation section for further information.