Aerius Use In Pregnancy & Lactation

Tablet/Syrup: No overall effect on rat fertility was observed with desloratadine at an exposure that was 34 times higher than the exposure in humans at the recommended clinical dose.
No teratogenic or mutagenic effects were observed in animal trials with desloratadine (see Pharmacology: Toxicology: Preclinical Toxicology under Actions). Since no clinical data on exposed pregnancies are available with desloratadine, the safe use of AERIUS tablets and syrup during pregnancy has not been established. AERIUS tablets and syrup are not to be used during pregnancy unless the potential benefits outweigh the risks.
Desloratadine is excreted into breast milk, therefore the use of AERIUS tablets and syrup are not recommended in breast-feeding women.
Oral solution: No teratogenic effects were observed in animal studies with desloratadine.
Since no clinical data on exposure during pregnancy are available with desloratadine, the safe use of desloratadine during pregnancy has not been established. Desloratadine should not be used during pregnancy unless the potential benefit outweighs the risks. Desloratadine passes into breast milk; therefore, breastfeeding is not recommended in lactating women taking desloratadine.