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Fertility: Data concerning effects of acetylcysteine on human fertility are not available. In animal studies, no harmful effects on fertility were observed for therapy-relevant doses of acetylcysteine (see Pharmacology: Toxicology: Preclinical safety data under Actions).
Pregnancy: There are no adequate clinical data from the use of acetylcysteine in pregnant women. Animal studies do not indicate direct or indirect harmful effects with respect to reproductive toxicity (see Pharmacology: Toxicology: Preclinical safety data under Actions). Whenever possible, use during pregnancy should be avoided and only take place after a strict benefit-risk assessment.
Breast-feeding: No information is available regarding excretion of acetylcysteine or its metabolites into breast milk. A risk for the breast-fed child cannot be excluded. Use during lactation should only take place after a strict benefit-risk assessment.
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