Varivax Dosage/Direction for Use

FOR SUBCUTANEOUS ADMINISTRATION.
Do not inject intravascularly.
Children: Children 12 months to 12 years of age should receive a 0.5 mL dose administered subcutaneously.
If a second 0.5 mL dose is administered, it should be given a minimum of 3 months later (see Pharmacology under Actions).
Adolescents and Adults: Adolescents and adults 13 years of age and older should receive a 0.5 mL dose administered subcutaneously at elected date and a second 0.5 mL dose 4 to 8 weeks later.
Refrigerator-stable VARIVAX is for subcutaneous administration. The outer aspect of the upper arm (deltoid region) is the preferred site of injection.
Methods of administration: Prefilled syringe of diluent: To reconstitute the vaccine, inject all of the diluent (0.7 mL) in the prefilled syringe into the vial of lyophilized vaccine and gently agitate to mix thoroughly. Withdraw the entire contents into the syringe and inject the total volume (about 0.5 mL) of reconstituted vaccine subcutaneously, preferably into the outer aspect of the upper arm (deltoid region) or the anterolateral thigh. It is recommended that the vaccine be administered immediately after reconstitution, to minimize loss of potency. Discard if reconstituted vaccine is not used within 30 minutes.
Do not freeze reconstituted vaccine.
Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit. VARIVAX (Refrigerated) when reconstituted is a clear, colorless to pale yellow liquid.
Vial of diluent: To reconstitute the vaccine, first withdraw 0.7 mL of diluent into a syringe. Inject all of the diluent in the syringe into the vial of lyophilized vaccine and gently agitate to mix thoroughly. Withdraw the entire contents into the syringe and inject the total volume (about 0.5 mL) of reconstituted vaccine subcutaneously, preferably into the outer aspect of the upper arm (deltoid region) or the anterolateral thigh. It is recommended that the vaccine be administered immediately after reconstitution, to minimize loss of potency. Discard if reconstituted vaccine is not used within 30 minutes.