IM/SCAdult & adolescent ≥13 yr Approx 0.5 mL dose at elected date & 2nd dose of approx 0.5 mL 4-8 wk later. Administer SC in patients w/ thrombocytopenia or any coagulation disorder. Childn 12 mth-12 yr Approx 0.5 mL dose. 2nd dose of approx 0.5 mL should be given a min of 3 mth later.
Hypersensitivity to any vaccine component including gelatin. History of anaphylactoid reaction to neomycin. Individuals w/ blood dyscrasias, leukemia, lymphomas of any type or other malignant neoplasms affecting bone marrow or lymphatic systems. Individuals receiving immunosuppressive therapy or on immunosuppressants; may result in more extensive vaccine-associated rash or disseminated disease in individuals on immunosuppressant doses of corticosteroids. Individuals w/ primary & acquired immunodeficiency states including those who are immunosuppressed in association w/ AIDS or other clinical manifestations of infection w/ HIV, cellular immune deficiencies & hypogammaglobulinemic & dysgammaglobulinemic states. Family history of congenital or hereditary immunodeficiency. Active untreated TB. Any febrile resp illness or other active febrile infection. Pregnancy.
Adequate treatment provisions including epinephrine inj should be available for immediate use if an anaphylactoid reaction occur. Do not inj intravascularly. Defer vaccination for at least 5 mth following blood/plasma transfusions or administration of immune globulin/varicella zoster immune globulin (VZIG). Do not give any immune globulin including VZIG for 2 mth thereafter following administration unless its use outweighs the benefits. Avoid salicylates for 6 wk after vaccination; possible Reye syndrome. Obtain previous immunization history of vaccinee. Defer vaccination in patients w/ family history of congenital or hereditary immunodeficiency until patient's own immune system has been evaluated. Avoid close association w/ susceptible high-risk individuals (eg, immunocompromised individuals, pregnant women & newborn infants of mothers w/o documented history of chickenpox or lab evidence of prior infection, all newborn infants born at <28 wk gestation regardless of maternal varicella immunity) for up to 6 wk. Avoid pregnancy for 3 mth following vaccination. Lactation. Childn & young adults who are known to be infected w/ HIV w/ & w/o immunosuppression evidence. Childn <1 yr; not recommended in infant <12 mth.
Co-administration w/ immune globulins, salicylates & blood/plasma transfusions. No data relating to simultaneous administration of refrigerator-stable Varivax w/ DPT or oral poliovirus vaccine.
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