Cyclopropane and halogenated hydrocarbon anaesthetics should be avoided.
MAO (monoamine oxidase) inhibitors potentiate the effect of dopamine and its duration of action. Patients who have been treated with MAO inhibitors prior to dopamine should be given reduced doses: the starting dose should be one tenth (1/10th) of the usual dose.
Dopamine-induced renal vasodilation can be antagonised by either α- or β-adrenergic blocking agents, e.g., phenothiazines, butyrophenones.
When guanethidine, tricyclic antidepressant, reserpine, sympathomimetics, thyroid hormone, antihistamines are administered with dopamine, the sympathomimetic action may increase.
The change of blood pressure may be induced by α- or β-adrenergic blocking agents.