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Dopamine should be infused into a large vein whenever possible to prevent the possibility of infiltration of perivascular tissue adjacent to the infusion site. lschemia can be reversed by infiltration of the affected area with 10-15ml of saline containing 5 to 10 mg adrenergic blocking agents.
Dopamine should not be added to any alkaline intravenous solutions, i.e. Sodium Bicarbonate.
Dilution in these fluids retains at least 95% if the original potency for 24 hours at room temperature. Dilutions should be discard immediately after use.
