ED (for as needed use) Adult male Recommended dose: 10 mg prior to anticipated sexual activity. Max dose: 20 mg once daily.
Renal impairment CrCl 31-50 mL/min Starting dose: 5 mg not more than once daily. Max dose: 10 mg not more than once in every 48 hr,
CrCl <30 mL/min or hemodialysis Max dose: 5 mg not more than once in every 72 hr.
Hepatic impairment Recommended dose: 10 mg taken prior to anticipated sexual activity.
Patient taking potent CYP3A4 inhibitors (eg, ketoconazole or ritonavir) Max dose: 10 mg, not to exceed once every 72 hr.
ED (for once daily use) Recommended starting dose: 2.5 mg once daily taken at approx the same time every day, w/o regard to timing of sexual activity. May be increased to 5 mg once daily, based on individual efficacy & tolerability.
Patient taking potent CYP3A4 inhibitors (eg, ketoconazole or ritonavir) Max dose: 2.5 mg.
BPH Recommended dose: 5 mg taken at approx the same time every day. In combination w/ finasteride: 5 mg taken at approx the same time every day for up to 26 wk.
ED & BPH Recommended dose: 5 mg taken at approx the same time every day, w/o regard to timing of sexual activity.