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Like other sympathomimetics, phentermine may interact with a number of drugs.
Phentermine should not be given to patients being treated with monoamine oxidase inhibitors or within 14 days of stopping such treatment.
Concurrent use of beta blockers and amphetamines may produce severe hypertension.
Patients receiving amphetamines and tricyclic antidepressants require careful monitoring as the risk of cardiovascular effects may be increased.
Concomitant use of sympathomimetics with volatile anaesthetics is associated with an increased risk of cardiac arrhythmias.
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