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Mefenamic acid should not be used in patients who have exhibited hypersensitivity to it. Because potential exists for cross-sensitivity to aspirin or other non-steroidal anti-inflammatory drugs, it should not be given to patients in whom these drugs induce symptoms of bronchospasm, allergic rhinitis or urticaria. Mefenamic acid is contraindicated in patients with active ulceration or chronic inflammation of either the upper or lower gastrointestinal tract. Mefenamic acid should be avoided in patients with pre-existing renal disease. Safety and effectiveness in children below the age of 14 have not been established.
This preparation should not be used in patients with glaucoma, achalasia, prostatic hypertrophy, obstruction of the bladder neck or myasthenia gravis.
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