Sign Out
Chronic inflammatory bowel disease and/or bowel obstruction (see Precautions).
History of severe hypersensitivity reactions to irinotecan hydrochloride trihydrate or to one of the excipients of Irinotecan Hydrochloride concentrate for solution for injection.
Lactation (see Use in Pregnancy & Lactation and Precautions).
Bilirubin > 3 times the upper limit of the normal range (see Precautions).
Severe bone marrow failure.
WHO performance status > 2.
In pregnant women.
