Iliadin Overdosage

The clinical picture following intoxication with imidazole-derivatives may be unclear due to the occurrence of episodes of hyperactivity alternated with episodes of depression of the central nervous system and of the cardiovascular and pulmonary system.
In children, in particular, overdose often causes dominating central nervous effects with convulsion and coma, bradycardia, apnoea as well as hypertension possibly followed by hypotension.
Therapeutic measure after overdosage: In-house intensive-care therapy is indicated in cases of severe overdose.
Administration of medicinal charcoal (absorbent), sodium sulfate (laxative) or gastric lavage (in the case of large quantities) should be performed immediately as oxymetazoline may be absorbed rapidly.
A non-selective alpha blocker can be given as antidote. If required, initiate fever-lowering measures, anticonvulsive therapy and oxygen ventilation.
Vasopressors are contraindicated.
Symptoms of an overdose may be hypertension, tachycardia, palpitations, cardiac arrhythmia, cardiac arrest, sweating, agitation, convulsion, mydriasis, nausea, vomiting, cyanosis, fever, spasms, circulatory collapse, pulmonary oedema, respiratory and psychic disorders, drowsiness, paleness, miosis, decrease in body temperature, bradycardia, shock-like hypotension, apnoea and coma.
Children drops/Adult drops: Overdosage may occur after nasal or accidental oral administration.