Aquipta Description

AQUIPTA Tablet 10 mg: AQUIPTA 10 mg is supplied as white to off-white, round biconvex tablets debossed with "A" and "10" on one side.
AQUIPTA Tablet 60 mg: AQUIPTA 60 mg is supplied as white to off-white, oval biconvex tablets debossed with "A60" on one side.
AQUIPTA is available as tablets for oral administration containing 10 mg or 60 mg atogepant.
The active ingredient of AQUIPTA is atogepant, a calcitonin gene-related peptide (CGRP) receptor antagonist. The chemical name of atogepant is (3'S)-N-[(3S,5S,6R)-6-methyl-2-oxo-1-(2,2,2-trifluoroethyl)-5-(2,3,6-trifluorophenyl)piperidin-3-yl]-2'-oxo-1',2',5,7-tetrahydrospiro[cyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridine]-3-carboxamide.
The molecular formula is C₂₉H₂₃F₆N₅O₃ and molecular weight is 603.5. Atogepant is a white to off-white powder. It is freely soluble in ethanol, soluble in methanol, sparingly soluble in acetone, slightly soluble in acetonitrile and practically insoluble in water.
Excipients/Inactive Ingredients: Colloidal silicon dioxide, croscarmellose sodium, mannitol, microcrystalline cellulose, polyvinylpyrrolidone/vinyl acetate copolymer, sodium chloride, sodium stearyl fumarate, vitamin E polyethylene glycol succinate.