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Folate-deficient megaloblastic anaemia: 5 mg daily for 4 mos. Up to 15 mg daily may be necessary in malabsorption states.
Chronic haemolytic states such as thalassaemia major or sickle-cell anaemia: 5 mg every 1 to 7 days.
Prophylaxis of folate deficiency in children on dialysis in children more than 12 years old: 5 to 10 mg daily.
For women of child-bearing potential at high risk of having pregnancy affected by neural tube defect, the dose of folic acid is 4 or 5 mg daily starting before pregnancy and continued through the first trimester. Or as prescribed by the physician.
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