Adverse effects include headache which results upon discontinuation of therapy; Other frequent effects include palpitations, tachycardia; dizziness, abnormal stool, diarrhea, dyspepsia, flatulence, nausea; infection and peripheral edema, asthenia; gastritis, myocardial infarction, congestive heart failure, postural hypotension, insomnia, anxiety, abnormal dream, dyspnoea, pneumonia, cough, hypersensitivity reactions, diabetes mellitus, anaemia, haemorrhage, thrombocythaemia, myalgia, renal impairment.