Vasalat Adverse Reactions

Calcium-channel blockers are normally avoided in patients with heart failure but amlodipine has not been found to have any adverse effects on morbidity or mortality in patients with severe heart failure receiving Vasalat. Therefore, it may be a suitable treatment for angina pectoris or hypertension in some patients.
Amlodipine is well-tolerated by most patients. In clinical trials in adults, the rate of discontinuation (1.5%) was no different than that of placebo. The most commonly reported adverse effects were headache, edema, dizziness, flushing and palpitations. Other adverse effects reported in 1-4% of patients receiving either amlodipine or placebo include: Fatigue, nausea, abdominal pain, somnolence; muscle cramps, pruritus and rash. The incidence of hypotension, arrhythmias and peripheral ischemia with amlodipine use was <1%. In post-marketing surveillance, gynecomastia and hepatic dysfunction (with jaundice and elevated hepatic transaminases) have been reported.
In pediatric reports, amlodipine has been associated with the development of edema, fatigue, flushing, headache, dizziness and nausea.