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Metabolic alkalosis (a serious disturbance characterized by an alkaline status of the body) may occur when given in large doses or in patients with impaired kidney function.
Milk-alkali syndrome characterized by hypercalcemia (excess calcium in the blood), and anorexia (loss of appetite) has been reported with chronic administration of Bicarbonate with milk or calcium.
Patients with low blood calcium levels may experience tetany when given Sodium Bicarbonate.
Sodium overload.
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