Unigan Special Precautions

In case severe, unexplained abdominal pain persists or worsens or occurs together with symptoms e.g. fever, nausea. vomiting, changes in bowel movements, abdominal tenderness, decreased blood pressure, fainting or blood in stool, medical advice should immediately be sought.
To prevent overdosing, ensure that any other drugs taken concurrently do not contain Paracetamol.
UNIGAN should be used with caution in glucose-6-phosphate-dehydrogenase (G6PD) deficiency, hepatic dysfunction (e.g. due to chronic alcohol abuse, hepatitis), impaired renal function. Gilbert's syndrome and hepatocellular insufficiency. In such cases, UNIGAN should only be used under medical supervision and, if necessary, the dose reduced or the intervals between the individual administrations prolonged.
The blood count and renal and liver function should be monitored after prolonged use.
Extensive use of analgesics, especially at high doses, may induce headaches that must not be treated with increased doses of UNIGAN. Severe acute hypersensitivity reactions (e.g. anaphylactic shock) are very infrequently observed. Treatment must be discontinued at the 1st signs of a hypersensitivity reaction following the administration of UNIGAN.
Liver damage may result if the recommended dosage is exceeded. Abrupt discontinuation of analgesic after prolonged use at high doses may induce withdrawal symptoms (e.g. headache, tiredness, nervousness), that typically resolve within few days. Reintake of analgesics should depend upon physician's advice and withdrawal symptoms abated.
UNIGAN should not be taken for >3 days unless directed by a physician. If pain persists or gets worse. if new symptoms occur or if redness or swelling is present, a physician should be consulted because these could be signs of a serious condition.
Because of the potential risk of anticholinergic complications, caution should be used in patients prone to narrow angle glaucoma as well as in patients susceptible to intestinal or urinary outlet obstructions and in those inclined to tachyarrhythmia.
Use in children: UNIGAN is not suitable for children <10 years.