Trinir Adverse Reactions

Cap: The adverse effects associated with cefdinir and other cephalosporins are broadly similar to those described for penicillins. The most common are hypersensitivity reactions, including skin rashes, urticaria, eosinophilia, fever, reactions resembling serum sickness and anaphylaxis.
There may be a positive response to the Coombs' test although hemolytic anaemia rarely occurs. Neutropenia and thrombocytopenia have occasionally been reported. Agranulocytosis has been associated rarely with some cephalosporins.
Postmarketing Experience: The following adverse experiences and altered laboratory tests, regardless of their relationship to Cefdinir, have been reported during extensive postmarketing experience, beginning with approval in Japan in 1991: shock, anaphylaxis with rare cases of fatality, facial and laryngeal edema, feeling of suffocation, serum sickness-like reactions, conjunctivitis, stomatitis, Stevens-Johnson syndrome, toxic epidermal necrolysis, exfoliative dermatitis, erythema multiforme, erythema nodosum, acute hepatitis, cholestasis, fulminant hepatitis, hepatic failure, jaundice, increased amylase, acute enterocolitis, bloody diarrhea, hemorrhagic colitis, melena, pseudomembranous colitis, pancytopenia, granulocytopenia, leukopenia, thrombocytopenia, idiopathic thrombocytopenic purpura, hemolytic anemia, acute respiratory failure, asthmatic attack, drug-induced pneumonia, eosinophilic pneumonia, idiopathic interstitial pneumonia, fever, acute renal failure, nephropathy, bleeding tendency, coagulation disorder, disseminated intravascular coagulation, upper GI bleed, peptic ulcer, ileus, loss of consciousness, allergic vasculitis, possible Cefdinir-diclofenac interaction, cardiac failure, chest pain, myocardial infarction, hypertension, involuntary movements and rhabdomyolysis.
Suspension: Adverse effects cannot be anticipated. Diarrhea, nausea, vaginal infection and rash. Use Cefdinir with caution if patient suffers from colitis (inflammation of the bowel). Cefdinir has been known to cause colitis. If patient develops symptoms such as diarrhea while taking this medication, notify the doctor. The use of an antibiotic to kill one type of germ can sometimes promote the growth of other germs that are resistant to the drug. If a new infection (called a superinfection) occurs, alert the doctor. Patient may need to take a different antibiotic. If patient suffers from seizures, use Cefdinir with caution. If patient had a seizure while using Cefdinir, stop taking it and call the doctor immediately. If patient ever had an allergic reaction to a cephalosporin antibiotic, he/she should not take this medication. Note, if patient is allergic to penicillin, he/she may also be allergic to cephalosporins. The reaction can be extremely severe. Be sure to let the doctor know about any allergies the patient may have.