Thrombotic Thrombocytopenia Purpura (TTP): Thrombotic thrombocytopenia purpura has been reported rarely following use of clopidogrel, sometimes after a short exposure (<2 weeks). It is a serious condition and requires urgent referral to a hematologist for prompt treatment. It is characterized by thrombocytopenia, microangiopathic hemolytic anemia [schistocytes (fragmented RBCs) seen on peripheral smear], neurological findings, renal dysfunction and fever.
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