Clopidogrel should be used with caution in patients receiving other drugs that increase the risk of bleeding, including anticoagulants, other antiplatelets and NSAIDs. Clopidogrel may inhibit the cytochrome P-450 isoenzyme CYP2C9 and interactions with drugs metabolized by this isoenzyme are theoretically possible. It may also inhibit CYP2B6.
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