Synalar 10/Synalar 25/Synalar HP Use In Pregnancy & Lactation

Synalar 10/Synalar 25: The use of any drug in pregnancy, lactation, or in women of childbearing age requires that the potential benefits of the drug be weighed against the possible hazards to the mother and child.
While topical corticosteroids have not been reported to have an adverse effect on human pregnancy, the safety of their use in pregnant women has not been established absolutely. Therefore, drugs of this class should not be used extensively on pregnant patients in large amounts or for prolonged periods of time, especially for the first three months of pregnancy.
Synalar HP: In laboratory animals, increase in incidences of fetal abnormalities have been associated with exposure of gestating females to topical corticosteroids, in some cases at rather low dosage levels. Although topical corticosteroids have not been reported to have an adverse effect on human pregnancy, the safety of their use in pregnant women has not been established absolutely. Therefore, drugs of this class should not be used extensively on pregnant patients, in large amounts or for prolonged periods of time, especially during the first three months of pregnancy.
It is not known whether topical administration of corticosteroids could result in sufficient systemic absorption to produce detectable quantities in breastmilk. Caution should be exercised when topical corticosteroids are administered to nursing woman.