Spiriva/Spiriva Respimat Dosage/Direction for Use

Spiriva: The recommended dosage of Tiotropium bromide (Spiriva) is inhalation of the contents of one capsule once daily with the HandiHaler inhalation device at the same time of day (see Instructions for Use/Handling under Cautions for Usage).
Tiotropium bromide (Spiriva) capsules must not be swallowed.
Special population: Elderly patients can use Tiotropium bromide (Spiriva) at the recommended dose.
Renally impaired patients can use Tiotropium bromide (Spiriva) at the recommended dose.
However, as with all predominantly renally excreted drugs, Tiotropium bromide (Spiriva) use should be monitored closely in patients with moderate to severe renal impairment. Hepatically impaired patients can use Tiotropium bromide (Spiriva) at the recommended dose.
Paediatric population: There is no experience with Tiotropium bromide (Spiriva) in infants and children and therefore should not be used in this age group.
Spiriva Respimat: The recommended dosage of Tiotropium bromide (Spiriva Respimat) is inhalation of the spray of two puffs once daily from the Respimat reusable inhaler at the same time of day (see Instructions for Use/Handling under Cautions for Usage).
In the treatment of asthma, the full benefits will be apparent after several doses of Tiotropium bromide (Spiriva Respimat).
Special populations: Elderly patients can use Tiotropium bromide (Spiriva Respimat) at the recommended dose. Renally impaired patients can use Tiotropium bromide (Spiriva Respimat) at the recommended dose. However, as with all predominantly renally excreted drugs, Tiotropium bromide (Spiriva Respimat) use should be monitored closely in patients with moderate to severe renal impairment. Hepatically impaired patients can use Tiotropium bromide (Spiriva Respimat) at the recommended dose.
Paediatric population: COPD does not normally occur in children.
In asthma, the recommended dosage of Tiotropium bromide (Spiriva Respimat) in patients 6 to 17 years of age is inhalation of the spray of two puffs once daily from the Respimat reusable inhaler, at the same time of day (see Instructions for Use/Handling under Cautions for Usage).
The efficacy and safety of Tiotropium bromide (Spiriva Respimat) in paediatric patients below 1 year of age with asthma has not been established.