Speeda Dosage/Direction for Use

To reconstitute the vaccine, introduce the diluent 0.5 mL into the vial of powder and shake thoroughly until the powder is dissolved completely. The solution should be homogenous, clear and free of any particles. Withdraw the solution in a syringe.
Intramuscular administration: The 0.5 mL dose of vaccine shall be injected intramuscularly in the deltoid in adults and in the anterio-lateral region of the thigh in infants and toddlers.
Do not inject in the gluteal region. Do not administer by the subcutaneous route.
Intradermal administration: The 0.1 mL dose of vaccine (per site) shall be injected intradermally in each deltoid.
Pre-exposure schedule: Primary vaccination: 3 injections on Day 0, Day 7, Day 28; Booster injection 1 year later, Booster injection every 5 years.
The injection schedule on Day 28 may be administered on Day 21.
Post-exposure schedule: Auxiliary therapy: The treatment of wound is very important and must be performed promptly after the bite. It is recommended firstly to wash the wound with large quantities of water and soap and with detergent and then apply 75% alcohol, tincture of iodine or a 0.1% quaternary ammonium solution provided no soap remains as the two products neutralize each other.
Curative vaccination must be administered under medical supervision and only in rabies treatment centre.
Vaccination of non-immunized subjects: Intramuscular schedule (Standard intramuscular regimen: ESSEN): Five injections (0.5 mL) will be given intramuscularly on day 0, 3, 7, 14 and 28.
Intradermal schedule (Modified TRC-ID regimen, 2-2-2-0-2): One dose of vaccine, in a volume of 0.1 mL is given intradermally at two different sites, usually the left and right upper arm on day 0, 3, 7, and 28.
In the case of type III, anti-rabies immunoglobulin should be administered as well on day 0. The anti-rabies immunoglobulin (20 IU/kg) should be used as local wound soakage injection as much as possible, with the rest part for muscle injection. The rabies vaccine should be administered in different injection site.
In case of the following situation, the vaccine dose should be reduplicated on day 0 and 3.
The chronic patients suffered from tuberculosis or hepatocirrhosis have been vaccinated immunoglobulin or antiserum the day before the rabies vaccine injection or earlier.
The people whose wounded site is close to central nerve.
The patients who suffered from congenital or acquired immunity deficiency.
The elders.
The people who haven't been inoculated rabies vaccine after exposure.
Vaccination of immunized subjects: The people who have got the pre-exposure full course immunity within one year; they should be administrated one dose of vaccine on day 0 and 3 respectively in case of another exposure.
The people who have got the pre-exposure immunity and the booster immunity one year later within three years; they should be administered one dose of vaccine on day 0 and 3 respectively in case of another exposure.
The people who have got the pre-exposure immunity but didn't get booster injection after one year, or the people who have got post-exposure full course immunity one year before; they should get full course vaccination in case of another exposure.
The people who have got the pre-exposure immunity and the booster immunity one year later but it is over 3 years; they should get full course vaccination in case of another exposure.