RiteMED Meropenem Trihydrate Caution For Usage

Directions for Use, Compatibility and Stability: Prior to administration, parenteral drug products should be inspected visually for particulate matter and discoloration whenever solution and container permit.
Shake the reconstituted solution before use.
Observe strict aseptic technique when drawing up the contents of the vial. If contaminated, it has the potential to become a source of infection to patients.
For IV Bolus Administration: To reconstitute, dissolve meropenem powder for injection in the required amount of sterile Water for Injection as shown as follows. Shake to dissolve and let stand until clear. (See Table 6.)

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For IV Infusion: Meropenem for IV infusion may be directly reconstituted with a compatible infusion fluid. Alternatively, an injection vial may be reconstituted (as previously for IV Bolus), then the resulting solution added to an IV container and further diluted with an appropriate infusion fluid. (See Table 7.)

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Compatibility of meropenem with other drugs has not been established.
Do not mix with or add to solutions containing other drugs.
It is recommended to use freshly prepared solutions of IV meropenem.
Do not freeze meropenem solutions.