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As the possibility of interactions cannot be excluded, caution should be exercised when Glucosamine is used with other medicines.
Elevations in International Normalized Ratio (INR) serum values and potentiation of anticoagulant effects have been observed following concomitant use of Glucosamine and Warfarin. If concomitant therapy is necessary the patient's INR should be closely monitored.
Glucosamine may increase insulin resistance and consequently affect glucose tolerance. Diabetics, who under medical advice, decide to use Glucosamine supplements will need their blood glucose monitored and doses of antidiabetic medications adjusted.
Glucosamine may reduce the effect of chemotherapy drugs such as Doxorubicin, Etoposide and Teniposide.
