Remopain Special Precautions

Contraindication in patients with history of hypersensitivity to ASA or any other NSAIDs.
NSAIDs are contraindicated in patients with previous or active peptic ulceration.
Use with cautions in patients with cardiac, liver and renal disease.
Dose adjustments like using the lowest effective dose and monitoring of renal and liver functions should be instituted.
Should be used cautiously in patients receiving anticoagulant therapy and patients with hemophilia.
Hematological effects: ketorolac inhibits thrombocyte aggregation and prolongs bleeding time. Because of that ketorolac should not be used before surgery and use with caution if there are hemostasis disturbances.
Hepatic effects: ketorolac therapy increases hepatic enzymes and in hepatic disease patients, severe hepatic risk reaction may occur. Administration of ketorolac should be discontinued if abnormality of hepatic function test occurs after ketorolac administration.
Ketorolac trometamol is not recommended for children under 16 years (safety and efficacy have not been established).