Remopain Adverse Reactions

Side effect incidence increases proportionally with increasing dose of ketorolac. Severe complications are caused by ketorolac therapy eg, ulcer, bleeding and gastrointestinal perforation, postoperative bleeding, acute renal failure, anaphylactic and anaphylactoid reactions and hepatic failure must be kept on guard. Complications of NSAIDs may be serious, especially if administration of ketorolac is not in the recommended dose.
The adverse reactions listed as follows are reported as probably related to ketorolac in clinical trials: Incidence >1%: Percentage incidence was reported in ≥3% patients: Body as a Whole: Edema (4%).
Cardiovascular: Hypertension.
Dermatologic: Pruritus, rash.
Gastrointestinal: Nausea (12%), dyspepsia (12%), gastrointestinal pain (13%), diarrhea (7%), constipation, flatulence, gastrointestinal fullness, vomiting and stomatitis.
Hematologic and Lymphatic: Purpura.
Central Nervous System: Cephalgia (17%), drowsiness (6%), dizziness (7%), swelling.
Pain on injection sites was reported by 2% of patients studied with multiple doses.
Incidence ≤1%: Body as a Whole: Increased weight, fever, infections, asthenia.
Cardiovascular: Palpitations, not for cardiovascular effects.
Dermatological: Urticaria.
Gastrointestinal: Gastritis, rectal bleeding, belch, anorexia, and/or increased appetite.
Hematologic and Lymphatic: Epistaxis, anemia, eosinophilia. Nervous System: Tremor, abnormal dreams, hallucinations, euphoria, extrapyramidal symptoms, vertigo, paresthesia, depression, insomnia, nervousness, excessive thirst, dry mouth, abnormal vision, difficulty to concentrate, hyperkinesis, stupor.
Respiratory: Dyspnea, lung edema, rhinitis, cough.
Sensory: Abnormal taste, abnormal or blurred vision, tinnitus, deafness. Urogenital: Hematuria, proteinuria, oliguria, urine retention, polyuria, increased urinary frequency.