Quanil Special Precautions

Must not be administered in conjunction with medications containing centrophenoxine. In case of persistent intracranial hemorrhage, it is recommended not to exceed the dose of 1000 mg of Citicoline daily.
Cholines are generally regarded as safe and appear to be well-tolerated. High intake of cholines may cause low blood pressure, steatorrhea (undigested fat in stool), nausea, vomiting, salivation, diarrhea, constipation, anorexia, dizziness (vertigo), sweating, insomnia and headache. Cholines can possibly trigger existing epilepsy. Dosages at the upper limit (UL) intake levels are contraindicated for person suffering from trimethylaminuria, Parkinson's disease, or kidney or liver disease.
Skin rash has been reported. A cold and cough were noted in patients taking citicoline in a trial. Choline should be used cautiously by people with kidney or liver disorders. Agitation, paranoia and severe depression have been reported. Use cautiously in patients with a history of depression.
Because choline is a product of the breakdown of succinylcholine, it may produce undesirable effects as the drug, like respiratory depression. A "fishy" odor has been associated with choline. Sweating and stunted growth may occur.