Treatment of patients w/ serious cerebral injuries of vascular traumatic nature w/ or w/o loss of consciousness; degenerative damages & chronic cerebral vascular injuries in senile dementia.
Do not co-administer w/ drugs containing centrophenoxine. Do not exceed 1,000 mg daily in case of persistent intracranial hemorrhage. May trigger existing epilepsy. Patients w/ history of depression. May produce side effects eg, resp depression; fishy odor; sweating & stunted growth. Pregnancy & lactation.
Decreased urinary excretion of carnitine in young adult women. Enhanced effect of choline in the brain w/ chronic treatment of lithium. Increased plasma conc of dopa. Diminished pools of all choline metabolites w/ MTX. Possible interaction w/ pentazocine. May intensify effects &/or toxicity w/ succinylcholine.