Precedex Description

Dexmedetomidine (Precedex) Concentrate for Intravenous Infusion is a sterile, nonpyrogenic solution suitable for intravenous infusion following dilution.
Dexmedetomidine hydrochloride is a central alpha₂-adrenergic agonist. Dexmedetomidine is the S-enantiomer of medetomidine. Dexmedetomidine hydrochloride chemical name is 1H-Imidazole, 4-[1-(2,3-dimethylphenyl)ethyl]-, monohydrochloride, (S). Dexmedetomidine has a molecular weight of 236.7 and the empirical formula is C₁₃H₁₆N₂·HCl.
Dexmedetomidine is a white or almost white powder that is freely soluble in water and has a pKa of 7.1. Its partition coefficient in-octanol: water at pH 7.4 is 2.89.
Dexmedetomidine (Precedex) Concentrate for Intravenous Infusion is intended to be used after dilution. It is supplied as a clear, colorless, isotonic solution with a pH between 4.5 to 7.0. The solution is preservative-free and contains no additives or chemical stabilizers.
Dexmedetomidine (Precedex) Concentrate for Intravenous Infusion: Each mL contains 118 mcg of Dexmedetomidine hydrochloride (equivalent to 100 mcg or 0.1 mg of Dexmedetomidine).